The Pan-American Highway isn't a particularly challenging road to negotiate. Not like it used to be, anyhow. It's paved these days, but it remains really, really long. It runs 19,000 miles between Ushuaia, Argentina, at the southern tip of South America, and Prudhoe Bay, Alaska, in the Arctic Circle.
https://www.hagerty.com/media/archived/argentina-to-alaska-1969-torino-380/